Queensland 271 (Burns 96, Siddle 4-62) and 2 for 90 beat Victoria 167 (Handscomb 81, Finch 50, Steketee 4-52) and 191 (Harris 62, Handscomb 53, Steketee 4-49) by eight wickets
Queensland's seamers helped inflict Victoria's first defeat of the season inside three days at the Gabba.
Michael Neser claimed the all-important wicket of Glenn Maxwell early on day three before Mark Steketee cleaned up the tail to finish with four scalps in the innings and eight for the match, and ensure the Bulls only needed to chase 88 to win.
They suffered two hiccups, losing Matt Renshaw and Usman Khawaja but Joe Burns and Charlie Hemphrey guided the side home.
Maxwell began the day on 29 hoping to add significantly to Victoria's overnight lead of 50 but Neser found his outside edge as he prodded at a ball wide of off on 35. The tail folded fairly quickly from there with Victoria losing their last five wickets for just 35 runs. Steketee took the last three of the innings.
Queensland's chase started steadily moving to 30 without loss before Renshaw was again caught behind the wicket. This time Scott Boland claimed him with a ball angled in from around the wicket and nipping away to take the edge as he pushed forward in defence, Peter Handcomb completed the catch at second slip.
Khawaja scored 18 of the next 23 runs before he was caught behind off James Pattinson. But Burns and Hemphrey completed the chase, with Burns named man of the match for his 96 and 24 not out on a bowler friendly surface.