Faf du Plessis will be sidelined for six weeks after suffering an acute lumbar disc injury in the third ODI against Bangladesh on Sunday. Du Plessis had to retire hurt on 91 and could not return to lead the team in the field.
He had already been ruled out of the two-match T20 series, which starts on Thursday, but will now also miss most of the domestic T20 competition with the aim to be fit for the inaugural four-day, day-night Test against Zimbabwe on Boxing Day.
In du Plessis' absence, JP Duminy will lead the T20 side, which also includes AB de Villiers and Hashim Amla.
Du Plessis' injury should not impact any international commitments with South Africa's calendar empty until Boxing Day. Thereafter, they will play eight home Tests, including three in a full visit by India that also features six ODIs and three T20s. As South Africa's all-format captain, du Plessis will be eager to be fully fit for that series.
He was also due to captain the Stellenbosch Kings in the inaugural edition of the T20 Global League, which was scheduled to start on November 3, but the tournament has been postponed. Instead, CSA have moved the franchise T20 competition into the same slot.
Du Plessis is the first high-profile player who won't take part in that event. According to the timeline, du Plessis should return in the first week of December, by which time the competition will be in its final two rounds. He may be able to take part in the playoffs in mid-December.
His franchise, Titans, are laden with international talent. Test opener Dean Elgar, recent international debutant Aiden Markram, de Villiers, wicket-keeper batsman Quinton de Kock and limited-overs regular Farhaan Behardien all play at SuperSport Park, while they also have Dale Steyn, Morne Morkel and Chris Morris. All three quicks are expected to make their comebacks from injury in the T20 tournament, alongside Lungi Ngidi, who returned from a back problem to take 6 for 37 in an ongoing first-class match against Lions at the Wanderers.