Largest margins in T20s by Innings, runs & wickets for Middlesex vs Somerset
By runs
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 79 runs | 0 | 205 | 17.4 | 20.0 | v Middlesex | Taunton | 4 Jul 2010 | Twenty20 | |
| 40 runs | 0 | 236 | 20.0 | 20.0 | v Middlesex | Taunton | 5 Jun 2011 | Twenty20 | |
| 38 runs | 0 | 213 | 18.0 | 18.0 | v Middlesex | Taunton | 29 Jul 2018 | Twenty20 | |
| 35 runs | 0 | 216 | 17.2 | 20.0 | v Somerset | Richmond | 4 Aug 2019 | Twenty20 | |
| 22 runs | 0 | 184 | 20.0 | 20.0 | v Middlesex | Taunton | 25 Jul 2014 | Twenty20 | |
| 21 runs | 0 | 208 | 20.0 | 20.0 | v Middlesex | Uxbridge | 16 Jul 2017 | Twenty20 | |
| 5 runs | 0 | 120 | 16.0 | 16.0 | v Middlesex | Taunton | 2 Jul 2021 | Twenty20 | |
| 4 runs | 0 | 93 | 9.0 | 9.0 | v Somerset | Lord's | 23 Jun 2016 | Twenty20 |
By wickets
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 9 wickets | 12 | 172 | 18.0 | 20.0 | v Middlesex | Uxbridge | 26 Jun 2015 | Twenty20 | |
| 9 wickets | 39 | 137 | 13.3 | 20.0 | v Middlesex | Taunton | 2 Jun 2023 | Twenty20 | |
| 9 wickets | 45 | 79 | 12.3 | 20.0 | v Middlesex | Lord's | 11 Jun 2024 | Twenty20 | |
| 8 wickets | 17 | 153 | 17.1 | 20.0 | v Somerset | The Oval | 18 Jun 2014 | Twenty20 | |
| 6 wickets | 18 | 227 | 17.0 | 20.0 | v Somerset | Taunton | 30 Aug 2019 | Twenty20 | |
| 5 wickets | 13 | 156 | 17.5 | 20.0 | v Middlesex | Lord's | 9 Jun 2010 | Twenty20 | |
| 4 wickets | 12 | 176 | 18.0 | 20.0 | v Middlesex | Lord's | 19 Jul 2018 | Twenty20 |
By balls remaining in the second innings
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 9 wickets | 45 | 79 | 12.3 | 20.0 | v Middlesex | Lord's | 11 Jun 2024 | Twenty20 | |
| 9 wickets | 39 | 137 | 13.3 | 20.0 | v Middlesex | Taunton | 2 Jun 2023 | Twenty20 | |
| 6 wickets | 18 | 227 | 17.0 | 20.0 | v Somerset | Taunton | 30 Aug 2019 | Twenty20 | |
| 8 wickets | 17 | 153 | 17.1 | 20.0 | v Somerset | The Oval | 18 Jun 2014 | Twenty20 | |
| 5 wickets | 13 | 156 | 17.5 | 20.0 | v Middlesex | Lord's | 9 Jun 2010 | Twenty20 | |
| 9 wickets | 12 | 172 | 18.0 | 20.0 | v Middlesex | Uxbridge | 26 Jun 2015 | Twenty20 | |
| 4 wickets | 12 | 176 | 18.0 | 20.0 | v Middlesex | Lord's | 19 Jul 2018 | Twenty20 | |
| 5 wickets | 5 | 138 | 19.1 | 20.0 | v Somerset | Taunton | 15 Jul 2016 | Twenty20 | |
| 5 wickets | 4 | 230 | 19.2 | 20.0 | v Middlesex | Taunton | 12 Jun 2025 | Twenty20 | |
| 2 wickets | 2 | 161 | 19.4 | 20.0 | v Middlesex | Lord's | 1 Jul 2022 | Twenty20 | |
| 5 wickets | 1 | 163 | 15.5 | 16.0 | v Middlesex | Taunton | 23 Jul 2017 | Twenty20 |
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