Largest margins by Innings, runs & wickets for CSA Provincial One-Day Challenge Division Two, 2021/22
By runs
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 189 runs | 0 | 274 | 24.1 | 50.0 | v Limpopo | East London | 20 Mar 2022 | Other OD | |
| 158 runs | 0 | 300 | 33.5 | 50.0 | v S West D | Benoni | 16 Mar 2022 | List A | |
| 101 runs | 0 | 252 | 35.3 | 50.0 | v S West D | Oudtshoorn | 18 Mar 2022 | List A | |
| 61 runs | 0 | 310 | 49.0 | 50.0 | v Easterns | Benoni | 11 Mar 2022 | Other OD | |
| 44 runs | 0 | 346 | 50.0 | 50.0 | v Mpumalanga | White River | 24 Mar 2022 | Other OD | |
| 31 runs | 0 | 264 | 50.0 | 50.0 | v Limpopo | Polokwane | 27 Mar 2022 | Other OD | |
| 21 runs | 0 | 252 | 48.5 | 50.0 | v Border | Pietermaritzburg | 27 Mar 2022 | List A | |
| 21 runs | 0 | 199 | 23.0 | 23.0 | v Limpopo | Kimberley | 3 Apr 2022 | Other OD |
By wickets
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 8 wickets | 193 | 63 | 17.5 | 50.0 | v Limpopo | Oudtshoorn | 23 Mar 2022 | Other OD | |
| 5 wickets | 42 | 239 | 43.0 | 50.0 | v Limpopo | Polokwane | 11 Mar 2022 | Other OD | |
| 5 wickets | 31 | 267 | 44.5 | 50.0 | v Northern Cpe | Pietermaritzburg | 21 Mar 2022 | List A | |
| 5 wickets | 82 | 193 | 36.2 | 50.0 | v Mpumalanga | White River | 30 Mar 2022 | Other OD | |
| 5 wickets | 41 | 173 | 43.1 | 50.0 | v Mpumalanga | Pietermaritzburg | 1 Apr 2022 | Other OD | |
| 5 wickets | 11 | 243 | 48.1 | 50.0 | v Easterns | Polokwane | 1 Apr 2022 | Other OD | |
| 5 wickets | 13 | 255 | 47.5 | 50.0 | v Northern Cpe | Pietermaritzburg | 8 Apr 2022 | List A | |
| 4 wickets | 10 | 264 | 48.2 | 50.0 | v Easterns | Kimberley | 18 Mar 2022 | List A | |
| 3 wickets | 48 | 258 | 42.0 | 50.0 | v Border | White River | 13 Mar 2022 | Other OD |
By balls remaining in the second innings
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 8 wickets | 193 | 63 | 17.5 | 50.0 | v Limpopo | Oudtshoorn | 23 Mar 2022 | Other OD | |
| 5 wickets | 82 | 193 | 36.2 | 50.0 | v Mpumalanga | White River | 30 Mar 2022 | Other OD | |
| 3 wickets | 48 | 258 | 42.0 | 50.0 | v Border | White River | 13 Mar 2022 | Other OD | |
| 5 wickets | 42 | 239 | 43.0 | 50.0 | v Limpopo | Polokwane | 11 Mar 2022 | Other OD | |
| 5 wickets | 41 | 173 | 43.1 | 50.0 | v Mpumalanga | Pietermaritzburg | 1 Apr 2022 | Other OD | |
| 5 wickets | 31 | 267 | 44.5 | 50.0 | v Northern Cpe | Pietermaritzburg | 21 Mar 2022 | List A | |
| 5 wickets | 13 | 255 | 47.5 | 50.0 | v Northern Cpe | Pietermaritzburg | 8 Apr 2022 | List A | |
| 5 wickets | 11 | 243 | 48.1 | 50.0 | v Easterns | Polokwane | 1 Apr 2022 | Other OD | |
| 4 wickets | 10 | 264 | 48.2 | 50.0 | v Easterns | Kimberley | 18 Mar 2022 | List A | |
| 2 wickets | 8 | 243 | 48.4 | 50.0 | v Border | Kimberley | 30 Mar 2022 | List A | |
| 6 wickets | 2 | 232 | 49.4 | 50.0 | v Northern Cpe | Oudtshoorn | 27 Mar 2022 | List A |
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