Largest margins by Innings, runs & wickets for Tamil Nadu Premier League, 2021
By runs
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 81 runs | 0 | 185 | 17.4 | 20.0 | v Tiruppur | Chennai | 2 Aug 2021 | Other T20 | |
| 76 runs | 0 | 186 | 18.4 | 20.0 | v Spartans | Chennai | 30 Jul 2021 | Other T20 | |
| 74 runs | 0 | 152 | 13.4 | 20.0 | v Nellai | Chennai | 21 Jul 2021 | Other T20 | |
| 36 runs | 0 | 160 | 20.0 | 20.0 | v Kovai | Chennai | 6 Aug 2021 | Other T20 | |
| 24 runs | 0 | 160 | 20.0 | 20.0 | v Dindigul | Chennai | 1 Aug 2021 | Other T20 | |
| 19 runs | 0 | 173 | 20.0 | 20.0 | v Madurai | Chennai | 28 Jul 2021 | Other T20 | |
| 16 runs | 0 | 165 | 20.0 | 20.0 | v Tiruppur | Chennai | 24 Jul 2021 | Other T20 | |
| 11 runs | 0 | 145 | 20.0 | 20.0 | v Madurai | Chennai | 7 Aug 2021 | Other T20 | |
| 8 runs | 0 | 184 | 20.0 | 20.0 | v Warriors | Chennai | 15 Aug 2021 | Other T20 | |
| 7 runs | 0 | 170 | 20.0 | 20.0 | v Nellai | Chennai | 8 Aug 2021 | Other T20 | |
| 2 runs | 0 | 163 | 20.0 | 20.0 | v Kovai | Chennai | 31 Jul 2021 | Other T20 |
By wickets
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 8 wickets | 11 | 172 | 18.1 | 20.0 | v Warriors | Chennai | 23 Jul 2021 | Other T20 | |
| 8 wickets | 24 | 104 | 16.0 | 20.0 | v Dindigul | Chennai | 13 Aug 2021 | Other T20 | |
| 7 wickets | 13 | 111 | 17.5 | 20.0 | v Tiruppur | Chennai | 29 Jul 2021 | Other T20 | |
| 6 wickets | 30 | 97 | 15.0 | 20.0 | v Dindigul | Chennai | 22 Jul 2021 | Other T20 | |
| 6 wickets | 18 | 146 | 17.0 | 20.0 | v Tiruppur | Chennai | 7 Aug 2021 | Other T20 | |
| 5 wickets | 12 | 202 | 18.0 | 20.0 | v Kovai | Chennai | 25 Jul 2021 | Other T20 | |
| 5 wickets | 15 | 144 | 17.3 | 20.0 | v Kovai | Chennai | 11 Aug 2021 | Other T20 |
By balls remaining in the second innings
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 6 wickets | 30 | 97 | 15.0 | 20.0 | v Dindigul | Chennai | 22 Jul 2021 | Other T20 | |
| 8 wickets | 24 | 104 | 16.0 | 20.0 | v Dindigul | Chennai | 13 Aug 2021 | Other T20 | |
| 6 wickets | 18 | 146 | 17.0 | 20.0 | v Tiruppur | Chennai | 7 Aug 2021 | Other T20 | |
| 5 wickets | 15 | 144 | 17.3 | 20.0 | v Kovai | Chennai | 11 Aug 2021 | Other T20 | |
| 7 wickets | 13 | 111 | 17.5 | 20.0 | v Tiruppur | Chennai | 29 Jul 2021 | Other T20 | |
| 5 wickets | 12 | 202 | 18.0 | 20.0 | v Kovai | Chennai | 25 Jul 2021 | Other T20 | |
| 8 wickets | 11 | 172 | 18.1 | 20.0 | v Warriors | Chennai | 23 Jul 2021 | Other T20 | |
| 6 wickets | 9 | 117 | 18.3 | 20.0 | v Spartans | Chennai | 1 Aug 2021 | Other T20 | |
| 8 wickets | 9 | 121 | 18.3 | 20.0 | v Spartans | Chennai | 5 Aug 2021 | Other T20 | |
| 4 wickets | 7 | 143 | 18.5 | 20.0 | v Spartans | Chennai | 28 Jul 2021 | Other T20 | |
| 5 wickets | 7 | 148 | 18.5 | 20.0 | v Dindigul | Chennai | 3 Aug 2021 | Other T20 | |
| 5 wickets | 7 | 125 | 18.5 | 20.0 | v Madurai | Chennai | 4 Aug 2021 | Other T20 | |
| 3 wickets | 6 | 138 | 19.0 | 20.0 | v Madurai | Chennai | 25 Jul 2021 | Other T20 | |
| 7 wickets | 5 | 133 | 19.1 | 20.0 | v Chepauk | Chennai | 8 Aug 2021 | Other T20 | |
| 5 wickets | 4 | 146 | 19.2 | 20.0 | v Warriors | Chennai | 27 Jul 2021 | Other T20 | |
| 7 wickets | 2 | 166 | 19.4 | 20.0 | v Chepauk | Chennai | 24 Jul 2021 | Other T20 | |
| 3 wickets | 1 | 149 | 19.5 | 20.0 | v Nellai | Chennai | 26 Jul 2021 | Other T20 | |
| 5 wickets | 1 | 154 | 19.5 | 20.0 | v Chepauk | Chennai | 10 Aug 2021 | Other T20 |
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