Largest margins by Innings, runs & wickets for Charlotte Edwards Cup - Southern Vipers
By runs
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 113 runs | 0 | 180 | 14.0 | 20.0 | v SE Stars | Brighton | 19 Jun 2024 | Women's T20 | |
| 31 runs | 0 | 156 | 20.0 | 20.0 | v Lightning | Southampton | 18 May 2022 | Other T20 | |
| 28 runs | 0 | 174 | 20.0 | 20.0 | v Storm | Southampton | 30 May 2024 | Women's T20 | |
| 19 runs | 0 | 172 | 20.0 | 20.0 | v Sunrisers | Chelmsford | 24 May 2024 | Women's T20 | |
| 18 runs | 0 | 192 | 20.0 | 20.0 | v Thunder | Worcester | 10 Jun 2023 | Women's T20 | |
| 18 runs | 0 | 138 | 20.0 | 20.0 | v Storm | Bristol | 9 Jun 2024 | Women's T20 | |
| 16 runs | 0 | 145 | 20.0 | 20.0 | v Diamonds | Leeds | 4 Jun 2023 | Women's T20 | |
| 11 runs | 0 | 127 | 20.0 | 20.0 | v Diamonds | Chester-le-Street | 21 May 2022 | Other T20 |
By wickets
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 8 wickets | 39 | 103 | 13.3 | 20.0 | v Thunder | Hove | 14 May 2022 | Other T20 | |
| 7 wickets | 35 | 106 | 14.1 | 20.0 | v Storm | Southampton | 26 May 2023 | Women's T20 | |
| 7 wickets | 34 | 115 | 14.2 | 20.0 | v The Blaze | Worcester | 10 Jun 2023 | Other T20 | |
| 7 wickets | 55 | 86 | 10.5 | 20.0 | v Thunder | Manchester | 7 Jun 2024 | Women's T20 | |
| 6 wickets | 27 | 95 | 15.3 | 20.0 | v Thunder | Manchester | 1 Jun 2022 | Other T20 | |
| 6 wickets | 10 | 142 | 18.2 | 20.0 | v Diamonds | Southampton | 4 Jun 2022 | Other T20 | |
| 6 wickets | 25 | 110 | 15.5 | 20.0 | v Sparks | Northampton | 11 Jun 2022 | Other T20 | |
| 5 wickets | 20 | 142 | 16.4 | 20.0 | v Lightning | Nottingham | 29 May 2022 | Other T20 | |
| 5 wickets | 31 | 115 | 14.5 | 20.0 | v Sunrisers | Hove | 7 Jun 2023 | Women's T20 | |
| 4 wickets | 23 | 112 | 16.1 | 20.0 | v Thunder | Southampton | 31 May 2023 | Women's T20 |
By balls remaining in the second innings
Winner | Margin | Balls Rem | Target | Overs | Max | Opposition | Ground | Match Date | Scorecard |
| 7 wickets | 55 | 86 | 10.5 | 20.0 | v Thunder | Manchester | 7 Jun 2024 | Women's T20 | |
| 8 wickets | 39 | 103 | 13.3 | 20.0 | v Thunder | Hove | 14 May 2022 | Other T20 | |
| 7 wickets | 35 | 106 | 14.1 | 20.0 | v Storm | Southampton | 26 May 2023 | Women's T20 | |
| 7 wickets | 34 | 115 | 14.2 | 20.0 | v The Blaze | Worcester | 10 Jun 2023 | Other T20 | |
| 5 wickets | 31 | 115 | 14.5 | 20.0 | v Sunrisers | Hove | 7 Jun 2023 | Women's T20 | |
| 6 wickets | 27 | 95 | 15.3 | 20.0 | v Thunder | Manchester | 1 Jun 2022 | Other T20 | |
| 6 wickets | 25 | 110 | 15.5 | 20.0 | v Sparks | Northampton | 11 Jun 2022 | Other T20 | |
| 4 wickets | 23 | 112 | 16.1 | 20.0 | v Thunder | Southampton | 31 May 2023 | Women's T20 | |
| 5 wickets | 20 | 142 | 16.4 | 20.0 | v Lightning | Nottingham | 29 May 2022 | Other T20 | |
| 6 wickets | 10 | 142 | 18.2 | 20.0 | v Diamonds | Southampton | 4 Jun 2022 | Other T20 | |
| 6 wickets | 7 | 170 | 18.5 | 20.0 | v SE Stars | Newbury | 23 May 2023 | Women's T20 | |
| 5 wickets | 7 | 146 | 18.5 | 20.0 | v Diamonds | Southampton | 14 Jun 2024 | Women's T20 |
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