Fudadin, 29, has played three Tests for West Indies, against New Zealand and England in 2012, when he made 122 runs in five innings with one half-century. He recently scored a century for West Indies A against Sri Lanka A in Moratuwa, in October.
The West Indies selectors also requested that fast bowler Sheldon Cottrell play for Jamaica in the third round of the Professional Cricket League so that they "have an opportunity to evaluate his match readiness," the board said in a release.
Cottrell had returned from the A tour of Sri Lanka with a hamstring injury. As a result, he will not leave for South Africa with the rest of the squad on November 30.
Test squad for South Africa: Denesh Ramdin (capt), Sulieman Benn, Jermaine Blackwood, Kraigg Brathwaite, Shivnarine Chanderpaul, Sheldon Cottrell, Assad Fudadin, Shannon Gabriel, Chris Gayle, Jason Holder, Leon Johnson, Kemar Roach, Marlon Samuels, Jerome Taylor, Chadwick Walton