William Porterfield will play his 200th game for Ireland when he leads his side against England in a solitary ODI on May 8.
Porterfield, the 30-year-old left-hander, is one of the longest-serving captains in world cricket and he will lead Ireland against what is expected to be a largely shadow XI for England, who will have completed a Test in the Caribbean three days earlier.
It will be Ireland's first fixture after Phil Simmons departed to take charge of West Indies. Ireland hope to have a new coach installed for the match.
Thirteen players who featured in the World Cup return for Ireland, plus experienced Middlesex seamer Tim Murtagh, who missed the tournament with a foot injury. Max Sorensen and Durham's Peter Chase are left out.
"It's a bit special for my 200th to be against England in front of an expected sell-out crowd," Porterfield said. "I've happy memories personally from the last time we played them in Dublin, scoring a century, although the result didn't go our way that day.
Chairman of selectors Alan Lewis admitted that they had opted for the tried and tested: "It was hard to bring any new faces in with it being so early in the season. We've named 14 in the squad rather than the usual 13 as there are some concerns over the fitness of Andrew McBrine, who was injured earlier this week.
"It's great to have Tim Murtagh back in the squad. He brings quality and experience to our attack, and there are fewer better exponents of swing bowling in early season conditions."
Ireland ODI squad: William Porterfield (capt), Andrew Balbirnie, Alex Cusack, George Dockrell, Ed Joyce, Andrew McBrine, John Mooney, Tim Murtagh, Kevin O'Brien, Niall O'Brien, Paul Stirling, Stuart Thompson, Gary Wilson, Craig Young